That stubborn fat around hips, buttocks and thighs for women, and the belly and side “love handles” for men, is every dieter’s biggest adversary. It is the last 10 pounds to go, and it is always the hardest to lose.
There are several theories why that stubborn fat is stored in different places for men and women. Some say it’s genetic. Your body stores fat where there are fat cells, and for most of us they concentrate on the upper and lower midsection. Exactly where the fat goes may depend on the lipoprotein lipase, which is an enzyme necessary for fat storage.
Women have more of this enzyme in the thighs and buttocks while men have higher concentrations in the abdomen.
It could also be related to hormone levels. Women with more estrogen tend to have a smaller waist to hip ratio, for instance. And postmenopausal women (who have low levels of estrogen) may feel like they are “spreading out” even as their weight remains the same.